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Filling an obvious gap in the scientific literature, this
practice-oriented reference is the first to tie together the
working knowledge of large
screening centers in the pharmaceutical and biotechnological field.
It spans the entire fi eld of this emerging discipline, from
compound
acquisition to collection optimization for specific purposes, to
technology and quality control. In so doing, it applies two decades
of expertise gathered by several large pharmaceutical companies to
current and future challenges in high-throughput screening. With
its treatment of libraries of small molecules as well as biobanks
containing biomolecules, microorganisms and tissue samples, this
reference is universally applicable for any molecular scientist
involved in a large screening program.
A conductor is one of classical music's most recognisable but
misunderstood figures, attracting so many questions:
'Surely orchestras can play perfectly well without you? '
'Do you really make any difference to the performance?'
'Are the musicians even watching you?'
The Silent Musician is not a manual for conductors, nor a history of
conducting. It is for all who wonder what conductors actually do, and
why they matter.
The conductor--tuxedoed, imposingly poised above an orchestra,
baton waving dramatically--is a familiar figure even for those who
never set foot in an orchestral hall. As a veritable icon for
classical music, the conductor has also been subjected to some
ungenerous caricatures, presented variously as unhinged
gesticulator, indulged megalomaniac, or even outright impostor.
Consider, for example: Bugs Bunny as Leopold Stokowski,
dramatically smashing his baton and then breaking into erratic
poses with a forbidding intensity in his eyes, or Mickey Mouse in
Fantasia, unwittingly conjuring dangerous magic with carefree
gestures he doesn't understand. As these cliches betray, there is
an aura of mystery around what a conductor actually does, often
coupled with disbelief that he or she really makes a difference to
the performance we hear. The Silent Musician deepens our
understanding of what conductors do and why they matter. Neither an
instruction manual for conductors, nor a history of conducting, the
book instead explores the role of the conductor in noiselessly
shaping the music that we hear. Writing in a clever, insightful,
and often evocative style, world-renowned conductor Mark
Wigglesworth deftly explores the philosophical underpinnings of
conducting--from the conductor's relationship with musicians and
the music, to the public and personal responsibilities conductors
face--and examines the subtler components of their silent art,
which include precision, charisma, diplomacy, and passion.
Ultimately, Wigglesworth shows how conductors--by simultaneously
keeping time and allowing time to expand--manage to shape ensemble
music into an immersive, transformative experience, without ever
making a sound.
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